Overview

This activity is designed to inform physicians about the adverse events observed when treating patients with targeted therapies as well as immunotherapies such as checkpoint inhibitors.

Target Audience

This activity is directed toward medical oncologists, dermatologists, pulmonary care specialists, endocrinologists, gastroenterologists, primary care physicians, nurses, and advanced practitioners who treat and/or manage cancer patients that are being treated with targeted therapies or checkpoint inhibitors. Surgical oncologists, radiation oncologists, pathologists, fellows, physician assistants, and other healthcare providers interested in the management of adverse events associated with targeted therapies and checkpoint inhibitors are also invited to participate.

Learning Objectives

After participating in this CME/CE activity, learners should be better prepared to:

• Compare and contrast the differences between adverse events from targeted- and immune-related therapies versus those seen with conventional cytotoxic chemotherapy
• Describe the impact of adverse events when targeted therapies or checkpoint inhibitors are combined
• Explain the correlation between immune-related adverse events and the overall survival
• Discuss strategies for managing frequently occurring toxicities from targeted therapies and checkpoint inhibitors

The American Journal of Hematology/ Oncology^® Editorial Board

Debu Tripathy, MD
Professor of Medicine and Chair
Department of Breast Medical Oncology
The University of Texas MD Anderson Cancer Center
Houston, TX
Disclosure: Grant/research support from Genentech/Roche, Pfizer, Puma Biotechnology Inc, and Novartis (clinical trial support contracted to the University of Southern California and MD Anderson Cancer Center); consultant for Eisai, OncoPlex Diagnostics, Merck, and Novartis.

Faculty

Mario E. Lacouture, MD
Director, Oncodermatology Program
Dermatology Service
Department of Medicine
Memorial Sloan Kettering Cancer Center
New York, NY
Disclosure: Grant Research/Support: Berg, Bristol-Myers Squibb, Genentech

Staff/Planner Disclosures and Conflict of Interest Resolution

The staff of Physicians' Education Resource^®, LLC, (PER^®) and the editorial staff of The American Journal of Hematology/Oncology^® have no relevant financial relationships with commercial interests to disclose.

It is the policy of PER^® to ensure fair balance, independence, objectivity, and scientific objectivity in all of our CME activities. In accordance with ACCME guidelines, PER^® requires everyone who is in a position to control the content of an educational activity, including spouses/partners, to disclose all relevant financial relationships with any commercial interest to participants as part of the activity planning process. PER^® has implemented mechanisms to identify and resolve all conflicts of interest prior to release of this activity.

Accreditation/Credit Designation

Physicians' Education Resource^®, LLC, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physicians' Education Resource^®, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physicians' Education Resource^®, LLC is approved by the California Board of Registered Nursing, Provider #16669 for 1.0 Contact Hour.

Acknowledgment of Commercial Support

This activity is funded by Physicians' Education Resource^®, LLC.

Off-Label Disclosure and Disclaimer

This continuing medical and nursing education activity may or may not discuss investigational, unapproved or off-label uses of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME/CE activity is for continuing medical and nursing education purposes only and is not meant to substitute for the independent medical judgment of a physician or nurse relative to diagnostic, treatment, and management options for a specific patient's medical condition.

Disclaimer

The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of Physicians' Education Resource^®, LLC. Contact information for questions about the activity:

Physicians' Education Resource^®, LLC
666 Plainsboro Road, Suite 356
Plainsboro, NJ 08536
Phone: (888) 949-0045
E-mail: [email protected]

Hardware And Software Requirements

• A Pentium-based PC or compatible computer
• At least 64MB of RAM
• Windows 95/98/NT/ME/2000/XP/Vista system software
• Screen resolution of 1024 x 786 or larger recommended
• PDF Reader: Adobe Reader 5.0 or higher, Foxit Reader 2.0 or likewise

• A PowerPC processor-based Macintosh computer
• At least 64MB of RAM
• Mac OS 7.5 or later
• Screen resolution of 1024 x 786 or larger recommended
• PDF Reader: Adobe Reader 5.0 or higher, Foxit Reader 2.0 or likewise