Accreditation/Credit Designation

Physicians’ Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Physicians’ Education Resource®, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Acknowledgment of Support

This activity is supported by educational grants from Amgen, Inc.; Karyopharm Therapeutics; Oncopeptides; and Sanofi Genzyme.

Clinical Vignette: Managing Multiple Myeloma From Newly Diagnosed to Relapsed/Refractory Settings: An Expert Case-Based Discussion

Release Date: November 30, 2021
Expiration Date: November 30, 2022

Activity Overview

Although multiple myeloma (MM) remains incurable, the past 15 years have yielded better clinical outcomes, and response rates have risen as high as 30% with monotherapy and up to 90% with combination therapies. Given the new treatments that offer the potential to improve progression-free survival and overall survival in these patients, keeping up to date on emerging clinical data is important for the selection and sequencing of therapy and the management of adverse events.

This activity provides hematologists and oncologists with a case-based review of recent clinical trials to allow them to incorporate new agents and regimens safely and appropriately and, thus, optimize the management of patients with MM throughout the course of the disease.

Acknowledgement of Commercial Support

This activity is supported by educational grants from Amgen, Inc.; Karyopharm Therapeutics; Oncopeptides; and Sanofi Genzyme.

Instructions for This Activity and Receiving Credit

  1. Complete the activity (including pre- and post-activity assessments).
  2. Answer the evaluation questions.
  3. Request credit using the drop-down menu.

You may immediately download your certificate.

Target Audience

This educational activity is directed toward hematologists, medical oncologists, nurse practitioners, nurses, and fellows who treat patients with MM. Physician assistants, pharmacists, researchers, and other health care professionals interested in the treatment of MM are also invited to participate.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

  • integrate patient-specific factors, risk stratification, and treatment history into individualized treatment plans for patients with newly diagnosed and relapsed/refractory MM
  • evaluate updated results from pivotal trials on current and emerging therapeutic approaches for the treatment of MM across multiple settings
  • develop strategies to identify and mitigate the negative impact of treatment-related toxicities in patients with MM
  • apply practice-changing evidence on single agent/combination approaches and updated guidelines to real-world case scenarios of patients with MM

Faculty, Staff, and Planners’ Disclosures

The staff of Physicians’ Education Resource®, LLC, have no relevant financial relationships with ineligible companies.


Pashtoon Kasi, MD, MS
Ajai Chari, MD
Director, Clinical Research, Multiple Myeloma Program
Associate Medical Director, Tisch Cancer Institute Clinical Trials Office
Professor of Medicine (Hematology and Medical Oncology) at the Icahn School of Medicine, Mt. Sinai New York

Disclosures: Grant Research Support: Janssen Pharmaceuticals, Celgene, Novartis Pharmaceuticals, Amgen, Inc., Pharmacyclics LLC, Seagen Inc., Takeda Oncology; Consultant: Janssen Pharmaceuticals, Celgene, Novartis Pharmaceuticals, Amgen, Inc., Bristol Myers Squibb, Karyopharm Therapeutics, Sanofi Genzyme, Seagen Inc., Oncopeptides, Takeda Oncology, Antengene, GlaxoSmithKline, Secura Bio, Shattuck Labs.

Pashtoon Kasi, MD, MS
Surbhi Sidana, MD
Assistant Professor of Medicine
Director, Myeloma Cellular Immunotherapy
Division of BMT & Cell Therapy
Stanford University
Stanford, CA

Disclosures: Grant Research Support: Amgen, Inc., Bristol Myers Squibb, Janssen Pharmaceuticals, Sanofi Genzyme. Consultant: Magenta Therapeutics, Janssen Pharmaceuticals, Bristol Myers Squibb.

PER® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any company that provided commercial support for this activity.

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