Accreditation/Credit Designation

Physicians’ Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Physicians’ Education Resource®, LLC, designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physicians’ Education Resource®, LLC is approved by the California Board of Registered Nursing, Provider #16669, for 1.0 Contact Hours.

Acknowledgment of Commercial Support

This activity is supported by educational grants from Grifols and Takeda Pharmaceuticals U.S.A., Inc.

Community Practice Connections™: Alpha-1 Antitrypsin Deficiency—Strategies to Optimize Screening, Diagnosis, and Management

Release Date: November 16, 2021
Expiration Date: November 16, 2022

Activity Overview

Alpha-1 antitrypsin deficiency (AATD) is one of the most common, well-understood genetic conditions. Nevertheless, it remains widely underdiagnosed due to general unawareness of the disease, complicated diagnostic algorithms, and the perception of limited treatment options available. Individuals with AATD are predisposed to diseases of the lung, liver, and skin. This Community Practice Connections™ program provides an in-depth review of key highlights from the Alpha-1 Antitrypsin Deficiency—Strategies to Optimize Screening, Diagnosis, and Management satellite symposium, held in October 2021. This unique and engaging multimedia activity is ideal for the community-based clinician and focuses on the practical aspects of managing patients with AATD as it puts recent clinical trial data into clinical context. The program is designed to provide information for those who did not attend the live meeting and to help reinforce learnings for those who did attend.

Acknowledgement of Commercial Support

This activity is supported by educational grants from Grifols and Takeda Pharmaceuticals U.S.A., Inc.

Instructions for This Activity and Receiving Credit

  1. Complete the activity (including pre- and post-activity assessments).
  2. Answer the evaluation questions.
  3. Request credit using the drop-down menu.

You may immediately download your certificate.

Target Audience

This educational program is directed toward pulmonologists, primary care providers, allergists, nurse practitioners, physician assistants, nurses, and other health care professionals involved in the care of patients with AATD.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

  • Describe the genetic etiology and pathophysiology of AATD
  • Perform diagnosis of patients with suspected AATD using recommended laboratory tests and clinical assessments.
  • Evaluate patient outcomes following treatment with augmentation therapy.
  • Apply knowledge of recommended diagnostic assessments and management strategies to patient scenarios.

Faculty, Staff, and Planners’ Disclosures

The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible companies.


Timothy Craig, DO
Timothy Craig, DO
Penn State College of Medicine Distinguished Educator
Professor of Medicine and Pediatrics
Director, Alpha-1 Foundation Clinical Resource Center; Allergy, Asthma, and Immunology Fellowship; Respiratory Allergy and Immunology Clinical Research Center; and Section of Allergy, Asthma, and Immunology
Division of Pulmonary Allergy and Critical Care Medicine
Penn State University
Hershey, PA

Disclosures: Grant/Research Support: Takeda, CSL Behring; Consulting: Grifols, Takeda, CSL Behring; Speakers’ Bureau: Grifols, Takeda, CSL Behring.

Igor Barjaktarevic, MD, PhD
Igor Barjaktarevic, MD, PhD
Assistant Professor
Medical Director, Chronic Obstructive Pulmonary Disease Program
Director of Bedside Ultrasound
Department of Medicine
Division of Pulmonary and Critical Care Medicine
David Geffen School of Medicine at University of California Los Angeles
Los Angeles, CA

Disclosures: Grant/Research Support: Amgen, Theravance, Viatris, GE Healthcare; Consultant: Astra Zeneca, GlaxoSmithKline, Verona Pharma, Grifols, Aerogen, Theravance, Viatris.

PER® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a healthcare professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any company that provided commercial support for this activity.

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