Accreditation/Credit Designation

Physicians’ Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Physicians’ Education Resource®, LLC, designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Acknowledgment of Commercial Support

This activity is supported by an educational grant from Exact Sciences Corporation.

Advances In™: Testing and Treatment of Metastatic CRPC with PARP Inhibitors

Release Date: November 30, 2021
Expiration Date: November 30, 2022

Activity Overview

It is estimated that more than 248,000 men will be diagnosed with prostate cancer (PC) in 2021. PC is a complex and heterogeneous disease and as such, determining the best treatment approach is convoluted. With advances in DNA analysis and targeted agents, biomarker testing has provided clinicians with additional parameters regarding patient- and tumor-specific factors that can improve risk stratification and treatment decision-making.
This online educational activity is designed to provide expert interpretation of new and emerging data on the treatment of metastatic castration-resistant prostate cancer (mCRPC) with PARP inhibitors with a forward-looking perspective on how new and novel agents might impact clinical practice. The essentials of biomarkers tests and testing guidelines, current and emerging PARP inhibitors for the management of CRPC, and management of treatment-related toxicities will be presented in a multimedia format, including a series of video interviews with expert thought leaders integrated into text-based elements.

Acknowledgement of Commercial Support

This activity is supported by an educational grant from Exact Sciences Corporation.

Instructions for This Activity and Receiving Credit

  1. Complete the activity (including pre- and post-activity assessments).
  2. Answer the evaluation questions.
  3. Request credit using the drop-down menu.

You may immediately download your certificate.

Target Audience

This educational program is directed toward medical oncologists, surgical oncologists, and urologists interested in the treatment of prostate cancer. Nurse practitioners, physician assistants, nurses, and other healthcare professionals involved in the treatment and management of patients with prostate cancer will be invited to participate.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

  • Outline molecular and biomarker testing guidelines in the context of guiding care in metastatic castration-resistant prostate cancer (mCRPC) settings.
  • Evaluate clinical trial evidence from investigations that have evaluated PARP inhibitors for the treatment of mCRPC.
  • Formulate strategies to monitor for and mitigate the impact of adverse events associated with PARP inhibitor approaches utilized among men with prostate cancer.
  • Integrate PARP inhibitor therapy into personalized care plans for the treatment of mCRPC.

Faculty, Staff, and Planners’ Disclosures

The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible companies.


Joseph Tauber, MD
David I Quinn, MD, MBBS, PhD, FRACP, FACP
Head, Section of GU Oncology
Associate Professor of Medicine
Division of Oncology
USC Norris Comprehensive Cancer Center
Keck School of Medicine of USC
Medical Director
USC Norris Comprehensive Cancer Center
Los Angeles, CA

Disclosures: Grant/Research Support: Merck, Pfizer, Genentech; Consultant: Astellas, Merck, Bayer, Roche/Genentech, Novartis, BMS

PER® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a healthcare professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any company that provided commercial support for this activity.

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