Accreditation/Credit Designation

Physicians’ Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Physicians’ Education Resource®, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Acknowledgment of Commercial Support

This activity is supported by an educational grant from Agios Pharmaceuticals, Inc.

Advances In™: Clinical Impact of Novel Emerging Treatment Options for PK Deficiency

Release Date: December 20, 2021
Expiration Date: December 20, 2022

Activity Overview

This online educational activity is designed to provide expert interpretation of new and emerging data on the diagnosis and treatment of pyruvate kinase deficiency, with a forward-looking perspective on how new and novel agents might impact clinical practice. An overview of the disease, optimal strategies to diagnose this rare hemolytic anemia, current management strategies, a focus on emerging strategies (including data on PK activators and gene therapy), and the importance of a multidisciplinary team approach in managing this disease will be presented in a multimedia format, including a series of video interviews with an expert thought leader integrated into text-based elements.

Acknowledgement of Commercial Support

This activity is supported by an educational grant from Agios Pharmaceuticals, Inc.


Instructions for This Activity and Receiving Credit

  1. Complete the activity (including pre- and post-activity assessments).
  2. Answer the evaluation questions.
  3. Request credit using the drop-down menu.

You may immediately download your certificate.

Target Audience

This educational activity is directed toward hematologists, hematologist/oncologists, nurses, and genetic counselors interested in the treatment of rare hematologic disorders.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

  • Describe the clinical presentation and pathophysiology as well as diagnostic strategies of PKD
  • Explain current standards of care and unmet needs in patients with PKD
  • Determine how patient-centered multidisciplinary and counseling strategies can be implemented along the disease continuum among patients who receive care for PKD
  • Assess the impact of recent clinical trial evidence in the context of evolving treatment paradigms in the field of PKD management

Faculty, Staff, and Planners’ Disclosures

The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible companies.


Hanny Al-Samkari, MD
Hanny Al-Samkari, MD
Classical Hematologist and Clinical Investigator
Division of Hematology Oncology
Massachusetts General Hospital
Assistant Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Disclosures: Grant/Research Support: Agios, Dova/Sobi, Amgen; Consultant: Agios, Dova/Sobi, Novartis, Argenx, Rigel, Moderna.

PER® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any company that provided commercial support for this activity.

Login or Register to Start Activity

Please use the form below to Register or Log In to begin Activity.

*Required Fields
Calendar of Events
Filter By